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Ramesh Parimi, Senior Consultant – Surgical Oncology, Specialist in Cancer Surgery Introduction An essential water-soluble vitamin, vitamin B12, also known as cobalamin, plays a major role in many fundamental biological processes to preserve health

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These structure-activity studies confirmed that the α-helical pharmacophore conformation stabilised by the disulphide bridge is equally critical for adipocyte target engagement in the N-terminally extended AOD9604 structure